The duo head Aridia where they save Skid McMarx, his agent, and gain a hoverboard, a Hydrodisplacer, and infobot showing a race Rilgar. They head there and came first in the race, and met a man in search of holocards detailing plans for a weapon called the RYNO. They head the research station Blarg, where they acquire an Infiltrator, Magneboots, and discover that Drek experimenting on a Blargian SnaggleBeast as a biological weapon. They overcome, acquiring a infobot Nefarious warn his troops a new experimental jetpack on Gaspar. They head there and get a pair of Grindboots. The only way to get the Jetpack is helping a neutral Blarg collect brains Telepathopuses; collect enough reward with Jetpack and Infotbot detailing an attack on Batalia by the forces of Drek. With Cora, they head to the planet and use a Planetary Defense Cannon to destroy warships. They also found another infobot, the Grim Ratchet asked to head Pokitaru and help his brother. They head there to find Blarg siphoning the planet of its water. With the help of his brother Grim and Big Al, who was on the planet for a convention, their upgrade Ratchet’s ship to destroy siphoning vessels. Al upgrades Clank with a booster pack.
With all their missions carried out, the duo head back to Kerwan where Qwark goes over a plan to infiltrate the factory Drek Quartu and take him. While Elaris, the support person of the Ranger and Clank think they should think of a plan, the rest decide to go full-on assault. They infiltrate the factory and, after defeating a giant Ms. Zurkon, Ratchet, Clank, and Cora discover the plan of Drek: he plans to use a superweapon called the station Deplanetizer destroy worlds and take their pieces to make Drek own perfect world. They follow the gun to Novalis and Qwark penetrates only trying to “talk” Drek of his madness. Rangers suspect something is wrong and go on the offensive. Ratchet infiltrates the station while Clank fights Victor on their mother ship, the Phoenix, defeat if the use of the sprinkler system. Ratchet tries to close the gun, but Drek incapacitating him. While his guards escorting a rescue capsule, Ratchet finds Qwark betrayed them switch sides to join the Blarg because of his jealousy to the heroism of Ratchet. Ratchet is run away and Novalis is destroyed Qwark giving second thoughts.